Vaccine Conversations: Dr. Shimi Sharief talks natural vs. vaccine-induced immunity

We continue to hear questions online about what the key differences between natural and vaccine-induced immunity are. To get some answers to those questions, we sat down with OHA Senior Health Advisor Dr. Shimi Sharief, who shared some insights on the topic. You can find a recording of the full interview, as well as a list of timestamped questions below. 

0:18 – What’s the difference between natural and vaccine-induced immunity? 

0:44 – Is either form of immunity better than the other? 

1:12 – How long does either form of immunity last? 

1:45 – If someone has had COVID-19, should they still get vaccinated? 

3:00 – What’s the risk of getting exposed to COVID-19 and how does it compare to getting vaccinated against COVID-19? 

4:01 – What are the chances of someone having serious complications from COVID-19 if they’re unvaccinated? What are the chances of someone having serious complications from COVID-19 if they’re fully vaccinated? 

5:40 – If someone is experiencing long-haul symptoms from COVID-19, will those symptoms clear up once they have completed a vaccine series?  

6:25 – Are there any other benefits to completing a COVID-19 vaccine series? 

8:07 – Anything else you would want to say to someone who is still on the fence to get vaccinated against COVID-19? 

Vaccination is the safest and most effective way for all people in Oregon to get back to doing the things they love. If you are 12 or older, visit OHA’s Find a COVID-19 Vaccine in Oregon webpage to schedule your vaccine appointment today.


  1. Interim Guidance on Ending Isolation and Precautions for Adults with COVID-19 – Centers for Disease Control and Prevention (CDC) 
  1. Lasting immunity found after recovery from COVID-19 – National Institutes of Health (NIH)